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Question papers>MAHE>2003>Pathology

1] Squamous cell carcinoma spreads commonly via :

1. Implantation
2. Hematogenous spread
3. Lymphatic spread
4. Transcoelomic spread

Ans :C

2] All are true regarding Pheochromocytoma except :

1. 10% are malignant
2. 10% are bilateral
3. 10% are pigmented
4. 10% are familial

Ans : C [ [pheochromocytoma is known as 10% tumor]

3] In "Wegener's granulomatosis" cytoplasmic anti-neutrophilic antibodies are directed against :

1. Proteinase 1
2. Proteinase 2
3. Proteinase 3
4. Proteinase 4

Ans : C [proteinase 3 is a serine protinase]

4] Commonest cause of non-healing ulcer of nipple

1. Paget's disease
2. CA-breast
3. Traumatic
4. Infective

Ans : A

5] A patient c/o a throbbing frontal headache. A cord like subcutaneous abnormality in the right side of his head is biopsed. Histological findings are "a large artery with focal areas of granulomatous inflammation in its wall& giant cells around fragments of mural elastic lamina. Most likely diagnosis :

1.   Wallerian degenaration of nerve.
2. Temporal vasculitis
3. Helmenthic infection
4. Ganglion cysts

Ans : B

6] The malignant breast tumor that mimics fibrodenoma is:

1. Phelloides tumor
2. Infiltrating duct adenoma
3. Infiltrating lobular adenocarcinoma
4. None of the above

Ans : A

7] The most common malignant brain tumor in children is:

1. Schwannoma
2. Medulloblastoma
3. Menegioma
4. Sq.cell CA

Ans : B

8] Regarding aplastic anemia all the following are true except

1. Patients have an acellular or markedly hypocellular bone marrow.
2. There is gradual replacement of Bone Marrow tissue by fibrous tissue.
3. It is caused by destruction of pleuripotent stem cells.
4. Fanconi's anemia is an example for aplastic anemia

Ans : B

9] Most commonest type of brain tumor in humans :

1. Menengioma
2. Glioma
3. Neural sheath tumor
4. Astriocytoma

Ans : B

10] All statements regarding eosinophils are true except :

1. Cells from the eosinophils series are anucleated bone marrow cells
2. Eosinophils are found in the GIT.
3. Eosinophils are found in the sub mucosa of respiratory tract.
4. Interleukin-5 directly stimulates the proliferation of eosinophils.

Ans :

11] Regarding "MAST CELLS" all are true except :

1. Mast cells contain Charcot-Leyden crystal protein
2. They are nucleated bone marrow cells
3. They have receptors for Fc portion of IgE.
4. They have peptidoglycan & chondritin sulphate

Ans :D

12] Raised PTH is found in :

1. Pseudohypoparathyroidism
2. Renal osteodystrophy
3. Hypercalcaemia
4. Osteogenisis imperfecta

Ans : B

13] All are tumor markers except :

1. Beta-microglobulin
2. HCG
3. Alfa-fetoproteins
4. CEA

Ans :A

14] Gamna gandy bodies contain hemosiderin & ...

1. Na+
2. Mg++
3. Zn++
4. Ca++

Ans :D

15] Hutchison's secondaries in the skull is due to :

1. Lung tumor
2. Breast tumor
3. Adrenal tumor
4. Testicular tumor

Ans : C

16] Albeno-cytologic dissociation occurs in :

1. Motor neurone disease
2. Demylinating disorder
3. Guillian-Barre syndrome
4. Neurocysticercosis

Ans : C

17] The term that describes the adherence of neutrophils & monocytes to the vascular endothelium before movement into extra vascular space :

1. Marginalization
2. Pavementing
3. Diapedisis
4. Migration

Ans : B