1]  One of the drugs listed below is contraindicated in the treatment of pregnancy induced hypertension :

1. Enalapril

2. Nifedpine

3. Magnesium Sulphate

4. Hydralazine

Ans : A

2] Sudden withdrawal of the following drug can cause serious adverse CVS changes in a patient taking the drug for a long time :

1. Phenelzine

2. Enalapril

3. Clonidine

4. Fluoxetine

Ans : C

3] Ideal drug employed in preoperative preparation of surgical excision of Pheochromocytoma is :

1. Atenolol

2. Phenoxybenzamine

3. Reserpine

4. Clonidine

Ans : B

4] Which of the following is a non-catecholamine sympathomimetic drug?

1. Ephidrine

2. Dopamine

3. Isoproterenol

4. Dobutamine

Ans : A

5] Which of the following is a specific antagonist of diazepam ?

1. Midazolam

2. Lorezipam

3. Flumazenil

4. Aminophylline

Ans : C

6] Which of the following do not cross the blood brain barrier?

1. Glycopyrrolate

2. Atropine

3. Scopolamine

4. Promethazine

Ans : A

7] In drug metabolism , hepatic cytochrome P-450 system is responsible for ...

1. Phase 1 reactions only ( hydrolysis , oxidation , reduction etc)

2. Phase 2 reactions only ( Conjugation Synthesis , etc )

3. Both A & B

4. Converting hydrophilic metabolites to lipophylic metabolites .

Ans : A

8] Short elimination half-life ( 8-10 min) of esmolol is due to ,

1.  Rapid redistribution

2. Rapid elimination from the kidneys

3. Hydrolysis by blood esterase's

4. Rapid protein binding

Ans : C

. .

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